Sussex Formulary

Drug Status Key

  • Non-Specialist Drugs
  • Specialist recommendation (or initiation where noted)
  • Specialist Initiation WITH Shared Care Guidelines
  • Specialist ONLY Drugs
  • Mixed Status - See individual drug entries for more details

Preferences

  • First Line
  • Second Line
  • Third Line
  • No Preference

Amsacrine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Arsenic trioxide

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Asparaginase

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Note that Erwina and E.coli asparaginases are not equivalent.

Spectrila 10,000unit powder for concentrate for solution for infusion vials

Pack
1 vial

Azacitidine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Bendamustine

{ Value = MHRA Warning Exists, Index = 4 } { Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Bexarotene

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Bleomycin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Busulfan

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Cabazitaxel

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Capecitabine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Carboplatin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Carmustine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Chlorambucil

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Leukeran is a branded option commissioned for prescribing.

Chlorambucil 2mg tablets

Pack
25 tablet
50 tablet

Chlorambucil 5mg tablets

Pack
25 tablet

Chlormethine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Cisplatin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Cladribine

{ Value = MHRA Warning Exists, Index = 4 } { Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Clofarabine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Approved for use in accordance with the National Cancer Drugs Fund List for the following indications, where the specified criteria are met: treatment of relapsed/refractory acute lymphoblastic leukaemia and treatment of relapsed/refractory acute myeloblastic leukaemia

Clofarabine 20mg/20ml solution for infusion vials

Pack
4 vial
1 vial

Cyclophosphamide

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Cyclophosphamide 25mg tablets

Pack
100 tablet
1 tablet

Cyclophosphamide 50mg tablets

Pack
100 tablet

Cyclophosphamide 25mg/5ml oral solution

Pack
1 ml
100 ml

Cyclophosphamide 35mg/5ml oral solution

Pack
1 ml

Cyclophosphamide 40mg/5ml oral solution

Pack
1 ml

Cyclophosphamide 50mg/5ml oral solution

Pack
1 ml

Cyclophosphamide 75mg/5ml oral solution

Pack
1 ml

Cyclophosphamide 100mg/5ml oral solution

Pack
1 ml
100 ml

Cyclophosphamide 25mg/5ml oral suspension

Pack
1 ml

Cyclophosphamide 35mg/5ml oral suspension

Pack
1 ml

Cyclophosphamide 40mg/5ml oral suspension

Pack
1 ml

Cyclophosphamide 50mg/5ml oral suspension

Pack
1 ml

Cyclophosphamide 75mg/5ml oral suspension

Pack
1 ml

Cyclophosphamide 100mg/5ml oral suspension

Pack
1 ml

Cyclophosphamide 200mg powder for solution for injection vials

Pack
1 vial

Cyclophosphamide 500mg powder for solution for injection vials

Pack
1 vial
10 vial

Cyclophosphamide 1g powder for solution for injection vials

Pack
1 vial
5 vial

Cyclophosphamide 2g powder for solution for injection vials

Pack
1 vial

Cyclophosphamide 480mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Cyclophosphamide 1000mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Cyclophosphamide 1120mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Cyclophosphamide 1260mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Cyclophosphamide 2000mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Cyclophosphamide 4180mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Cyclophosphamide 200mg/10ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 300mg/15ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 500mg/25ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 550mg/27.5ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 600mg/30ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 900mg/45ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 950mg/47.5ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cyclophosphamide 1g/50ml solution for infusion pre-filled syringes

Pack
1 pre-filled disposable injection
10 pre-filled disposable injection

Cytarabine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Dacarbazine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Daunorubicin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Doxorubicin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Epirubicin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Eribulin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Erwinase

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Note that Erwina and E.coli asparaginases are not equivalent.

Erwinase 10,000unit powder for solution for injection vials

Pack
5 vial

Estramustine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Estracyt is a branded option commissioned for prescribing.

Estramustine 140mg capsules

Pack
100 capsule

Etoposide

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Fludarabine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Fluorouracil

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Gemcitabine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Gemcitabine 1.2g/120ml infusion bags

Pack
1 bag

Gemcitabine 1.4g/140ml infusion bags

Pack
1 bag

Gemcitabine 1.6g/160ml infusion bags

Pack
1 bag

Gemcitabine 1.8g/180ml infusion bags

Pack
1 bag

Gemcitabine 2g/200ml infusion bags

Pack
1 bag

Gemcitabine 2.2g/220ml infusion bags

Pack
1 bag

Gemcitabine 1026mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1100mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1140mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1254mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1300mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1368mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1400mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1500mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1520mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1710mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 1900mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 2128mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 2394mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 2400mg/250ml in Sodium chloride 0.9% infusion bags

Pack
1 bag

Gemcitabine 200mg powder for solution for infusion vials

Pack
1 vial

Gemcitabine 1g powder for solution for infusion vials

Pack
1 vial

Gemcitabine 1.5g powder for solution for infusion vials

Pack
1 vial

Gemcitabine 2g powder for solution for infusion vials

Pack
1 vial

Gemcitabine 1g/10ml solution for infusion vials

Pack
1 vial

Gemcitabine 1g/25ml solution for infusion vials

Pack
1 vial

Gemcitabine 1g/26.3ml solution for infusion vials

Pack
1 vial

Gemcitabine 200mg/2ml solution for infusion vials

Pack
1 vial

Gemcitabine 200mg/5ml solution for infusion vials

Pack
1 vial

Gemcitabine 200mg/5.26ml solution for infusion vials

Pack
1 vial

Gemcitabine 200mg/5.3ml solution for infusion vials

Pack
1 vial

Gemcitabine 2g/20ml solution for infusion vials

Pack
1 vial

Gemcitabine 2g/50ml solution for infusion vials

Pack
1 vial

Gemcitabine 2g/52.6ml solution for infusion vials

Pack
1 vial

Hydroxycarbamide

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Siklos tablets is a branded option commissioned for prescribing in Coastal West Sussex only for Sickle Cell anaemia

Hydroxycarbamide 500mg capsules

Pack
100 capsule

Hydroxycarbamide 100mg tablets

Pack
60 tablet

Hydroxycarbamide 1g tablets

Pack
30 tablet

Idarubicin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Ifosfamide

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Irinotecan

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Lomustine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

CeeNU is a branded option commissioned for prescribing.

Lomustine 40mg capsules

Pack
20 capsule

Melphalan

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Mercaptopurine

{ Value = Shared Care, Index = 4 } { Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Suspension and tablet doses are not interchangeable.

Mixed formulary colour coding:

AMBER (Shared care): Autoimmune hepatitis and inflammatory bowel disease.

RED: All other indications.

Mercaptopurine 50mg tablets

Pack
25 tablet

Mercaptopurine 20mg/ml oral suspension

Pack
60 ml
100 ml

Methotrexate

{ Value = Shared Care, Index = 4 } { Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Mitomycin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Mitotane

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Mitotane 500mg tablets

Pack
100 tablet

Mitoxantrone

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Nelarabine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Oxaliplatin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Paclitaxel

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Paclitaxel albumin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Panobinostat

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Pemetrexed

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Pentostatin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Pixantrone

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Procarbazine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Raltitrexed

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Rasburicase

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Streptozocin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Tegafur + Gimeracil + Oteracil

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Temozolomide

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Thiotepa

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Tioguanine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Capsules and suspension are unlicensed. Tablets are licensed.

Tioguanine 40mg tablets

Pack
25 tablet

Tioguanine 10mg capsules

Pack
1 capsule

Tioguanine 50mg/5ml oral suspension

Pack
100 ml

Topotecan

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Trabectedin

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Treosulfan

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Tretinoin

{ Value = MHRA Warning Exists, Index = 4 } { Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Tretinoin 10mg capsules

Pack
100 capsule

Trifluridine + Tipiracil

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Vinblastine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Vinblastine, vincristine, vindesine, vinflunine and vinorelbine injections are for intravenous administration only. Inadvertent intrathecal administration can cause severe neurotoxicity, which is usually fatal.

Vinblastine 10mg powder for solution for injection vials

Pack
1 vial

Vinblastine 10mg/10ml solution for injection vials

Pack
5 vial

Vincristine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Vinblastine, vincristine, vindesine, vinflunine and vinorelbine injections are for intravenous administration only. Inadvertent intrathecal administration can cause severe neurotoxicity, which is usually fatal.

Vincristine 1mg/1ml solution for injection vials

Pack
1 vial
5 vial

Vincristine 2mg/2ml solution for injection vials

Pack
5 vial
1 vial

Vindesine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Vinblastine, vincristine, vindesine, vinflunine and vinorelbine injections are for intravenous administration only. Inadvertent intrathecal administration can cause severe neurotoxicity, which is usually fatal.

Vindesine 5mg powder for solution for injection vials

Pack
1 vial

Vinorelbine

{ Value = NICE, Index = 0 } { Value = EMC, Index = 3 }

Vinblastine, vincristine, vindesine, vinflunine and vinorelbine injections are for intravenous administration only. Inadvertent intrathecal administration can cause severe neurotoxicity, which is usually fatal.

Vinorelbine 20mg capsules

Pack
1 capsule

Vinorelbine 30mg capsules

Pack
1 capsule

Vinorelbine 10mg/1ml solution for infusion vials

Pack
10 vial
1 vial

Vinorelbine 50mg/5ml solution for infusion vials

Pack
10 vial
1 vial