Drug Status Key

  • Non-Specialist Drugs
  • Specialist recommendation (or initiation where noted)
  • Specialist Initiation WITH Shared Care Guidelines
  • Specialist ONLY Drugs
  • Mixed Status - See individual drug entries for more details

Preferences

  • First Line
  • Second Line
  • Third Line
  • No Preference

Insulins - Rapid acting

There should be no new initiations for the following insulins as they are due to be discontinued by the manufacturer(s) (dates advised below): 

Admelog® - March 2026

Levemir© Penfill - December 2026

Levemir© FlexPen - December 2026

Insulatard© Isophane - March 2025

NovoRapid© FlexTouch - March 2025

To avoid confusion, it is advisable to prescribe insulin by brand name.

Advantages of generic prescribing are that it is generally more cost-effective, however there are some circumstances in which it is preferable to prescribe by brand name. Broadly, these circumstances are where continuity of the same brand is important due to differences in bioavailability, where training differs between products and for biological medicines.

The intention is to avoid inadvertent switching between preparations where this may have a detrimental effect on patient care.

Patient familiarity with one brand of insulin is important; instructions for use vary between preparations and patient training is required.

GREEN - Only for initiation by prescribers in primary care working under the diabetes care Locally Commissioned Service (LCS) agreement. Please refer to information found on the level of competences page within the type 2 diabetes LCS, and ensure prescribing is in accordance with the LCS documented place in therapy

Diabetes LCS

To avoid confusion, it is advisable to prescribe insulin by brand name.

See individual entries for prescribing status.

Rapid acting insulin analoges

FIASP is a branded option commissioned for prescribing

Ultra-rapid action formulation

Pack
1 vial

FIASP is a branded option commissioned for prescribing

Ultra-rapid action formulation

Pack
5 cartridge

FIASP is a branded option commissioned for prescribing

Ultra-rapid action formulation

Pack
5 pre-filled disposable injection
Pack
5 pre-filled disposable injection
Pack
5 cartridge
Pack
5 cartridge

Biosimilar insulins are the preferred/first line for routine new initiations where appropriate

Pack
5 cartridge

Biosimilar insulins are the preferred/first line for routine new initiations where appropriate

Pack
5 pre-filled disposable injection

Biosimilar insulins are the preferred/first line for routine new initiations where appropriate

Pack
1 vial

To avoid confusion, it is advisable to prescribe insulin by brand name.

See individual entries for prescribing status.

Rapid acting insulin analoges

Apridra is a branded option commissioned for prescribing.

GREEN - Coastal West Sussex.

PURPLE - Brighton & Hove and Crawley, Horsham & Mid-Sussex.

NOT COMMISSIONED - East Sussex.

Pack
5 cartridge

Apridra is a branded option commissioned for prescribing.

GREEN - Coastal West Sussex.

PURPLE - Brighton & Hove and Crawley, Horsham & Mid-Sussex.

NOT COMMISSIONED - East Sussex.

Pack
5 pre-filled disposable injection

Apridra is a branded option commissioned for prescribing.

GREEN - Coastal West Sussex.

PURPLE - Brighton & Hove and Crawley, Horsham & Mid-Sussex.

NOT COMMISSIONED - East Sussex.

Pack
1 vial

Unlicensed.

 

Pack
2 pre-filled disposable injection
5 pre-filled disposable injection

Hypurin vials not available for new initiations due to discontinuation:

Hypurin Porcine Neutral discontinuation date: 30 November 2025.

Hypurin Porcine 30/70 Mix discontinuation date: 31 Jan 2026.

Pack
5 cartridge

To avoid confusion, it is advisable to prescribe insulin by brand name.

See individual entries for prescribing status.

Rapid acting insulin analoges

Biosimilar insulins are the preferred/first line for routine new initiations where appropriate

Pack
1 vial

Biosimilar insulins are the preferred/first line for routine new initiations where appropriate

Pack
5 cartridge

Biosimilar insulins are the preferred/first line for routine new initiations where appropriate

Pack
5 pre-filled disposable injection

Humalog is a branded option commissioned for prescribing.

Pack
5 cartridge

Humalog is a branded option commissioned for prescribing.

Please note: Kwikpen device is available in two strengths, 100units/ml and 200units/ml.

Pack
5 pre-filled disposable injection

Humalog is a branded option commissioned for prescribing.

Please note: Kwikpen device is available in two strengths, 100units/ml and 200units/ml.

Pack
5 pre-filled disposable injection

 Lyumjev® is a branded option commissioned for prescribing

 

Pack
1 vial

Lyumjev® is a branded option commissioned for prescribing

Pack
5 cartridge

Lyumjev® is a branded option commissioned for prescribing

Pack
5 pre-filled disposable injection

Lyumjev® is a branded option commissioned for prescribing

Please note: Kwikpen device is available in two strengths, 100units/ml and 200units/ml.

Pack
5 pre-filled disposable injection

Lyumjev® is a branded option commissioned for prescribing

Please note: Kwikpen device is available in two strengths, 100units/ml and 200units/ml.

Pack
5 pre-filled disposable injection