5.6.1 Coronavirus

For treating mild to moderate COVID-19 in adults who have a positive SARS-CoV-2 test, only if:

they have 1 or more risk factors for progression to severe COVID-19

and

both nirmatrelvir plus ritonavir is contraindicated or unsuitable

(NICE TA1056)

Pack
40 capsule

Nirmatrelvir plus ritonavir is recommended as an option for treating COVID‑19 in adults, only if they:

  • do not need supplemental oxygen for COVID‑19 and

  • have an increased risk for progression to severe COVID‑19, as defined in section 5. (TA878)

Pack
30 tablet

Where more than one biologic treatment is suitable, it is the responsibility of the provider to ensure the most cost-effective option is selected.

Biosimilars are available which should be used in line with local contracting agreements.

Originator - RoActemra

Biosmilar - Avtozma

Tocilizumab is recommended, within its marketing authorisation, as an option for treating COVID‑19 in adults who:
  • are having systemic corticosteroids and

  • need supplemental oxygen or mechanical ventilation (TA878

Pack
4 pre-filled disposable injection
Pack
4 pre-filled disposable injection
Pack
1 vial
Pack
1 vial
Pack
1 vial