Adjunctive therapy for partial onset seizures in accordance with NICE NG217

Pack
14 tablet
Pack
56 tablet
Pack
56 tablet
Pack
56 tablet
Pack
56 tablet
Pack
300 ml
Funded by NHSE in accordance with NICE

Pack
1 ml
100 ml
Pack
100 ml

GREEN - first choice for trigeminal neuralgia

PURPLE - epilepsy (as per NICE NG217) and prophylaxis of bipolar disorder unresponsive to lithium (Tegretol in Brighton & Hove and Crawley, Horsham and Mid Sussex)

Prophylaxis of bipolar: when stopping treatment, reduce the dose gradually over a period of at least 4 weeks.

Oral liquid reserved for those with swallowing difficulties or specific clinical need.
Pack
500 tablet
84 tablet
28 tablet
56 tablet
Pack
84 tablet
500 tablet
28 tablet
56 tablet
100 tablet
Pack
100 tablet
28 tablet
56 tablet
Pack
56 tablet
50 tablet
30 tablet
60 tablet
100 tablet
Pack
56 tablet
30 tablet
50 tablet
60 tablet
Pack
5 suppository
Pack
5 suppository
Pack
300 ml
50 ml
250 ml
Pack
84 tablet (6 x 14 tablets)
Pack
84 tablet (6 x 14 tablets)
Pack
56 tablet (4 x 14 tablets)
Pack
56 tablet (4 x 14 tablets)
Pack
56 tablet (4 x 14 tablets)

To be initiated in a tertiary epilepsy centre for focal onset seizures with or without secondary generalised seizures in adults with drug-resistant epilepsy that has not been adequately controlled with at least 2 antiseizure medicines

Pack
28 tablet
Pack
14 tablet
Pack
14 tablet
28 tablet
Pack
14 tablet
28 tablet
Pack
14 tablet
28 tablet
Pack
14 tablet
28 tablet

PURPLE - Brighton & Hove under specialist palliative care advice

RED - West Sussex and East Sussex

Pack
5 ampoule

Syrup reserved for paediatric use and those with swallowing difficulties or specific clinical need

Pack
56 capsule
112 capsule
50 capsule
60 capsule
Pack
200 ml
Pack
125 ml
250 ml
200 ml

GREEN - unlicensed use in migraines

PURPLE - epilepsies as per NG217 

Oral solution reserved for paediatric use and those with swallowing difficulties or specific clinical need

Pack
100 capsule
50 capsule
90 capsule
Pack
100 capsule
40 capsule
50 capsule
90 capsule
Pack
100 capsule
30 capsule
50 capsule
90 capsule
Pack
100 tablet
10 tablet
Pack
100 tablet
Pack
150 ml

Syrup reserved for paediatric use and those with swallowing difficulties or specific clinical need

Pack
14 tablet
56 tablet
Pack
56 tablet
14 tablet
Pack
14 tablet
56 tablet
Pack
56 tablet
Pack
200 ml
Switching between brands NOT recommended in epilepsy. Prescribe generically
Dispersible tablets for patients with swallowing difficulties or if compliance issues and administered by a carer
Prevention of depressive episodes associated with biopolar disorder - mental health recommendation only

Exposure to sodium-containing formulations of effervescent, dispersible and soluble medicines associated with significantly increased odds of adverse cardiovascular events compared with standard formulations of the same drug. Sodium-containing formulations should be prescribed with caution only if the perceived benefits outweigh these risks

Pack
21 tablet
42 tablet
56 tablet
30 tablet
14 tablet
60 tablet
28 tablet
Pack
56 tablet
42 tablet
30 tablet
14 tablet
28 tablet
84 tablet
Pack
56 tablet
30 tablet
28 tablet
60 tablet
Pack
56 tablet
30 tablet
28 tablet
60 tablet

Oral solution reserved for paediatric use and those with swallowing difficulties or specific clinical need

Pack
60 tablet
100 tablet
30 tablet
50 tablet
Pack
60 tablet
100 tablet
50 tablet
30 tablet
200 tablet
Pack
60 tablet
50 tablet
Pack
60 tablet
30 tablet
Pack
300 ml
150 ml
Crawley, Horsham and Mid Sussex, and Brighton & Hove - please see place-based non-LCS Permapanel Information Sheet
Specialist to prescribe until patient is stable and for minimum of 2-3 months
Pack
7 tablet
28 tablet
Pack
28 tablet
Pack
28 tablet
Pack
28 tablet
Pack
28 tablet
Pack
28 tablet

Please note the Elixir is a Category 1 anti-epileptic so patients should be maintained on specific brand (but choice of brand on formulary is unrestricted)

Phenobarbital 15mg/5ml elixir contains alcohol.
Some hospitals supply alcohol-free formulations of varying phenobarbital strengths
Pack
1000 tablet
28 tablet
Pack
28 tablet
Pack
28 tablet
250 tablet
Pack
500 ml

PURPLE - 30mg/mL injection and 60mg/mL injection for use as an anxiolytic/hypnotic

RED - 200mg/mL injection 

Pack
10 ampoule
Pack
10 ampoule
Pack
10 ampoule

PURPLE - treatment of epilepsies

RED - trigeminal neuralgia only

Pack
28 capsule
Pack
28 capsule
Pack
84 capsule
100 capsule
Pack
28 capsule
Pack
1000 tablet
28 tablet
100 tablet
Pack
500 ml
250 ml
GREEN - third line for neuropathic pain only if patient successfully achieves pain relief with gabapentin but cannot tolerate side effects

PURPLE - treatment in epilepsies

To be prescribed generically

Solution for use in patients who cannot open pregabalin capsules or have swallowing difficulties. Patients should be reviewed if liquid is no longer needed and switched back to capsules if appropriate

High abuse potential

Use twice daily dosing as flat pricing structure
Pack
56 capsule
84 capsule
100 capsule
14 capsule
Pack
84 capsule
56 capsule
21 capsule
Pack
56 capsule
14 capsule
100 capsule
250 capsule
Pack
84 capsule
21 capsule
56 capsule
Pack
56 capsule
14 capsule
100 capsule
250 capsule
Pack
84 capsule
21 capsule
56 capsule
Pack
56 capsule
Pack
56 capsule
Pack
473 ml
500 ml
Pack
100 tablet
Pack
100 tablet
60 tablet
90 tablet
30 tablet
Pack
100 tablet
50 tablet
Pack
100 tablet
50 tablet
Pack
100 tablet
50 tablet

GREEN - prophylactic treatment of adult migraine

PURPLE - treatment in epilepsies

Topiramate is now contraindicated in pregnancy and in women of childbearing potential unless the conditions of a Pregnancy Prevention Programme are fulfilled. This follows a review by the MHRA which concluded that the use of topiramate during pregnancy is associated with significant harm to the unborn child. Harms included a higher risk of congenital malformation, low birth weight and a potential increased risk of intellectual disability, autistic spectrum disorder and attention deficit hyperactivity disorder in children of mothers taking topiramate during pregnancy. Please see latest MHRA information for advice.

Pack
60 capsule
Pack
60 capsule
Pack
60 capsule
Pack
60 tablet
28 tablet
Pack
60 tablet
28 tablet
56 tablet
Pack
60 tablet
28 tablet
56 tablet
Pack
60 tablet
28 tablet
56 tablet
Pack
14 capsule
56 capsule
Pack
56 capsule
28 capsule
Pack
56 capsule
65 capsule