Where more than one biologic treatment is suitable, it is the responsibility of the provider to ensure the most cost-effective option is selected.

Afqlir is the preferred biosimilar brand of aflibercept. All new patients should only be initiated on Afqlir.

  • Originator – Eylea
  • Biosimilar – Afqlir

Aflibercept 30.1mg/263microlitres (Eylea HD/Eylea 8mg) is indicated for neovascular (wet) Age-related Macular Hegeneration (nAMD) and Diabetic Macular Oedema (DMO) ONLY

Pack
1 vial
Pack
1 vial
Pack
1 pre-filled disposable injection
Pack
1 vial
Pack
1 pre-filled disposable injection

Where more than one biologic treatment is suitable, it is the responsibility of the provider to ensure the most cost-effective option is selected.
Biosimilars are available which should be used in line with local contracting agreements.

Originator - Lecentis
Biosimilars - Byooviz; Ongavia ; Ranivisio; Rimmyrah ; Ximluci 

Pack
1 pre-filled disposable injection
Pack
1 vial
Pack
1 vial

Bevacizumab gamma is recommended as an option for treating wet age-related macular degeneration in adults (as per NICE TA1022), only if:

    • the eye has a best-corrected visual acuity between 6/12 and 6/96

    • there is no permanent structural damage to the central fovea

    • the lesion size is 12 disc areas or less in greatest linear dimension

    • there are signs of recent disease progression (for example, blood vessel growth as shown by fluorescein angiography, or recent visual acuity changes)

Pack
1 vial