Drug Status Key

Non-Specialist Drugs
Specialist recommendation (or initiation where noted)
Specialist Initiation WITH Shared Care Guidelines
Specialist ONLY Drugs
Mixed Status - See individual drug entries for more details

Preferences

First Line
Second Line
Third Line
No Preference

Atidarsagene autotemcel

{ Value = NICE, Index = 0 }

{ Value = EMC, Index = 3 }

Commissioned by specialist commissioning

Atidarsagene autotemcel 2million-10million cells/ml dispersion for infusion bags

Pack
1 bag

Autologous cartilage cells

{ Value = NICE, Index = 0 }

{ Value = EMC, Index = 3 }

Commissioned by specialist commissioning

Characterised autologous human cartilage cells 4million cells/0.4ml implantation suspension vials

Pack
1 vial

Benzbromarone

{ Value = NICE, Index = 0 }

{ Value = EMC, Index = 3 }

Benzbromarone 100mg tablets

Pack
30 tablet
100 tablet
1 tablet

Onasemnogene

{ Value = NICE, Index = 0 }

{ Value = EMC, Index = 3 }

Commissioned by specialist commissioning

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 10.1-10.5kg) solution for infusion 7 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 10.6-11.0kg) solution for infusion 2 x 5.5ml + 6 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 11.1-11.5kg) solution for infusion 1 x 5.5ml + 7 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 11.6-12.0kg) solution for infusion 8 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 12.1-12.5kg) solution for infusion 2 x 5.5ml + 7 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 12.6-13.0kg) solution for infusion 1 x 5.5ml + 8 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 13.1-13.5kg) solution for infusion 9 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 13.6-14.0kg) solution for infusion 2 x 5.5ml + 8 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 14.1-14.5kg) solution for infusion 1 x 5.5ml + 9 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 14.6-15.0kg) solution for infusion 10 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 15.1-15.5kg) solution for infusion 2 x 5.5ml + 9 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 15.6-16.0kg) solution for infusion 1 x 5.5ml + 10 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 16.1-16.5kg) solution for infusion 11 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 16.6-17.0kg) solution for infusion 2 x 5.5ml + 10 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 17.1-17.5kg) solution for infusion 1 x 5.5ml + 11 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 17.6-18.0kg) solution for infusion 12 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 18.1-18.5kg) solution for infusion 2 x 5.5ml + 11 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 18.6-19.0kg) solution for infusion 1 x 5.5ml + 12 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 19.1-19.5kg) solution for infusion 13 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 19.6-20.0kg) solution for infusion 2 x 5.5ml + 12 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 2.6-3.0kg) solution for infusion 2 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 20.1-20.5kg) solution for infusion 1 x 5.5ml + 13 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 20.6-21.0kg) solution for infusion 14 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 3.1-3.5kg) solution for infusion 2 x 5.5ml + 1 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 3.6-4.0kg) solution for infusion 1 x 5.5ml + 2 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 4.1-4.5kg) solution for infusion 3 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 4.6-5.0kg) solution for infusion 2 x 5.5ml + 2 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 5.1-5.5kg) solution for infusion 1 x 5.5ml + 3 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 5.6-6.0kg) solution for infusion 4 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 6.1-6.5kg) solution for infusion 2 x 5.5ml + 3 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 6.6-7.0kg) solution for infusion 1 x 5.5ml + 4 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 7.1-7.5kg) solution for infusion 5 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 7.6-8.0kg) solution for infusion 2 x 5.5ml + 4 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 8.1-8.5kg) solution for infusion 1 x 5.5ml + 5 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 8.6-9.0kg) solution for infusion 6 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 9.1-9.5kg) solution for infusion 2 x 5.5ml + 5 x 8.3ml vials

Pack
1 pack

Onasemnogene abeparvovec 20 tera vector genomes/ml (patient weight 9.6-10.0kg) solution for infusion 1 x 5.5ml + 6 x 8.3ml vials

Pack
1 pack

Denosumab

{ Value = NICE, Index = 0 }

{ Value = EMC, Index = 3 }

Denosumab - For prevention of osteoporotic fractures in postmenopausal women:

All new patients should be initiated on a biosimilar product.
Biosimilar brands approved for local use: Stoboclo (Celltrion), Jubbonti (Sandoz), Junod (Gedeon Richter)
Patients discharged from hospital after being started on a different denosumab biosimilar (such as Zadenvi® locally) or the originator product Prolia® should be switched to the locally preferred products in line with agreed guidance.

Denosumab Patient Information Leaflet

Jubbonti 60mg/1ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection

Junod 60mg/1ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection

Stoboclo 60mg/1ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection

Zadenvi 60mg/1ml solution for injection pre-filled syringes

Pack
1 pre-filled disposable injection